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BDBM37755 1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one::3-hydroxy-1-(2-morpholinoethyl)-5-phenyl-4-(2-thenoyl)-3-pyrrolin-2-one::3-hydroxy-1-[2-(4-morpholinyl)ethyl]-5-phenyl-4-(2-thienylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one::4-hydroxy-1-(2-morpholin-4-ylethyl)-2-phenyl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one::4-hydroxy-1-[2-(4-morpholinyl)ethyl]-3-[oxo(thiophen-2-yl)methyl]-2-phenyl-2H-pyrrol-5-one::MLS000062692::SMR000071229::cid_2909953

SMILES: O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1

InChI Key: InChIKey=SKNWNDQUULIBLE-UHFFFAOYNA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 37755   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37755
PNG
(1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-th...)
Show SMILES O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1
Show InChI InChI=1/C21H22N2O4S/c24-19(16-7-4-14-28-16)17-18(15-5-2-1-3-6-15)23(21(26)20(17)25)9-8-22-10-12-27-13-11-22/h1-7,14,17-18H,8-13H2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
>4.03E+4n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM37755
PNG
(1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-th...)
Show SMILES O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1
Show InChI InChI=1/C21H22N2O4S/c24-19(16-7-4-14-28-16)17-18(15-5-2-1-3-6-15)23(21(26)20(17)25)9-8-22-10-12-27-13-11-22/h1-7,14,17-18H,8-13H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
>4.37E+4n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NZ862K
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37755
PNG
(1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-th...)
Show SMILES O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1
Show InChI InChI=1/C21H22N2O4S/c24-19(16-7-4-14-28-16)17-18(15-5-2-1-3-6-15)23(21(26)20(17)25)9-8-22-10-12-27-13-11-22/h1-7,14,17-18H,8-13H2
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>6.67E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM37755
PNG
(1-(2-morpholin-4-ylethyl)-4-oxidanyl-2-phenyl-3-th...)
Show SMILES O=C(C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccccc1)c1cccs1
Show InChI InChI=1/C21H22N2O4S/c24-19(16-7-4-14-28-16)17-18(15-5-2-1-3-6-15)23(21(26)20(17)25)9-8-22-10-12-27-13-11-22/h1-7,14,17-18H,8-13H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>6.67E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2J67FB5
More data for this
Ligand-Target Pair