BDBM377637 3-({[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]amino}methyl)-::US10266495, Compound I-49

SMILES O=c1[nH]c2ccccc2cc1CNc1ccc(cc1)-n1cnnn1

InChI Key InChIKey=IIMGWBMBLASITC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377637   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM377637(US10266495, Compound I-49 | 3-({[4-(1H-1,2,3,4-tet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent