BDBM378302 (2R,4S)-N-(1-(1-(L-alanyl)piperidin-4-yl)ethyl)-4-hydroxypyrrolidine-2-carboxamide::US10266526, Compound 433

SMILES: C[C@H](N)C(=O)N1CCC(CC1)C(C)NC(=O)[C@H]1C[C@H](O)CN1

InChI Key: InChIKey=FFMVOBMOMXPHEU-FZMOHWGLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM378302 ((2R,4S)-N-(1-(1-(L-alanyl)piperidin-4-yl)ethyl)-4-...) Show SMILES C[C@H](N)C(=O)N1CCC(CC1)C(C)NC(=O)[C@H]1C[C@H](O)CN1 Show InChI InChI=1S/C15H28N4O3/c1-9(16)15(22)19-5-3-11(4-6-19)10(2)18-14(21)13-7-12(20)8-17-13/h9-13,17,20H,3-8,16H2,1-2H3,(H,18,21)/t9-,10?,12-,13+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme Inc US Patent					Assay Description The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....				US Patent US10266526 (2019) BindingDB Entry DOI: 10.7270/Q2DJ5HX2
					More data for this Ligand-Target Pair