BDBM378370 1-(2-amino-2-oxoethyl)-N-((1r,4r)-4-aminocyclohexyl)-1H-1,2,3-triazole-4-carboxamide::US10266526, Compound 501

SMILES N[C@H]1CC[C@@H](CC1)NC(=O)c1cn(CC(N)=O)nn1

InChI Key InChIKey=DDKZTKLRIIJFEN-ZKCHVHJHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378370   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM378370(1-(2-amino-2-oxoethyl)-N-((1r,4r)-4-aminocyclohexy...)
Affinity DataIC50:  5.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent