BDBM378462 6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluorobutyl)piperidin-4-yl)methyl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)indoline-5-carboxamide::US10266526, Compound 595

SMILES: FC(F)(F)CCCN1CCC(CS(=O)(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)NC(=O)c2cc3CC(=O)Nc3cc2Cl)CC1

InChI Key: InChIKey=OTEIUEJPHNOGBG-UHFFFAOYSA-N

Data: 2 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 378462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM378462 (6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair