BDBM378686 1-cyclopropyl-N-{1-[(4-hydroxyphenyl)methyl]azetidin-3-yl}-1H-1,2,3-triazole-4-carboxamide::US10266526, Compound 824

SMILES: Oc1ccc(CN2CC(C2)NC(=O)c2cn(nn2)C2CC2)cc1

InChI Key: InChIKey=RITFLQDETUXYLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM378686 (1-cyclopropyl-N-{1-[(4-hydroxyphenyl)methyl]azetid...) Show SMILES Oc1ccc(CN2CC(C2)NC(=O)c2cn(nn2)C2CC2)cc1 Show InChI InChI=1S/C16H19N5O2/c22-14-5-1-11(2-6-14)7-20-8-12(9-20)17-16(23)15-10-21(19-18-15)13-3-4-13/h1-2,5-6,10,12-13,22H,3-4,7-9H2,(H,17,23)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	882	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme Inc US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...				US Patent US10266526 (2019) BindingDB Entry DOI: 10.7270/Q2DJ5HX2
					More data for this Ligand-Target Pair