BDBM378686 1-cyclopropyl-N-{1-[(4-hydroxyphenyl)methyl]azetidin-3-yl}-1H-1,2,3-triazole-4-carboxamide::US10266526, Compound 824

SMILES Oc1ccc(CN2CC(C2)NC(=O)c2cn(nn2)C2CC2)cc1

InChI Key InChIKey=RITFLQDETUXYLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378686   

TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM378686(1-cyclopropyl-N-{1-[(4-hydroxyphenyl)methyl]azetid...)
Affinity DataIC50:  882nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent