BDBM379033 2-[2,4-dichloro-3- ({3-[5-methoxy-4- (pyridin-4- ylamino)pyrimidin- 2-yl]-1H-indazol-1- yl}methyl)phenyl] propan-2-ol::US10266548, Example 9-3
SMILES COc1cnc(nc1Nc1ccncc1)-c1nn(Cc2c(Cl)ccc(c2Cl)C(C)(C)O)c2ccccc12
InChI Key InChIKey=CXQUQWTYKPPBHZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 379033
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 23nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair