BDBM379048 Preparation of 5-(cyclopropyloxy)-2-[1-(4-methoxybenzyl)-1H-indazol-3-yl]-N-(pyridin-4-yl)pyrimidin-4-amine::US10266548, Example 14-1

SMILES COc1ccc(Cn2nc(-c3ncc(OC4CC4)c(Nc4ccncc4)n3)c3ccccc23)cc1

InChI Key InChIKey=JALFYGLWDDGNBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379048   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM379048(Preparation of 5-(cyclopropyloxy)-2-[1-(4-methoxyb...)
Affinity DataIC50:  3.30E+3nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent