BDBM379697 US9926281, Compound 255

SMILES: C[C@H]1CN(CCN1c2cc(cc(c2)F)F)C(=O)CC[C@@]3(C(=O)NC(=O)N3)C4CC4

InChI Key: InChIKey=CMLVKUWQFZQPPS-UHFFFAOYSA-N

Data: 18 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 379697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 4 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
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A disintegrin and metalloproteinase with thrombospondin motifs 13 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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A disintegrin and metalloproteinase with thrombospondin motifs 5 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
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A disintegrin and metalloproteinase with thrombospondin motifs 5 (Mouse)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-14 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ADAMTS5 (Rat)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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A disintegrin and metalloproteinase with thrombospondin motifs 1 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
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A disintegrin and metalloproteinase with thrombospondin motifs 5 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-14 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Collagenase 3 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
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Interstitial collagenase (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Human)	BDBM379697 (US9926281, Compound 255) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair