BDBM380486 US9926318, 1-4::US9926318, 1-5::US9926318, 1-6::US9926318, C114

SMILES OC(=O)CCN1C(=O)C2Cc3c(CN2C1=O)n(Cc1ccc(F)cc1)c1ccccc31

InChI Key InChIKey=FARUMNUOOCOIFR-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 380486   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM380486(US9926318, 1-4 | US9926318, 1-5 | US9926318, 1-6 |...)
Affinity DataIC50: <500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM380486(US9926318, 1-4 | US9926318, 1-5 | US9926318, 1-6 |...)
Affinity DataIC50: <500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM380486(US9926318, 1-4 | US9926318, 1-5 | US9926318, 1-6 |...)
Affinity DataIC50: <500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM380486(US9926318, 1-4 | US9926318, 1-5 | US9926318, 1-6 |...)
Affinity DataIC50: <500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB