BDBM380925 Ethanesulfonic acid [8-(3-chloro-1H- indazol-6-yl)-3,4-dihydro-1H- pyrano[4,3-c]pyridin-4-yl]-amide, Enantiomer II::US9890171, 129

SMILES CCS(=O)(=O)NC1COCc2c1cncc2-c1ccc2c(Cl)n[nH]c2c1

InChI Key InChIKey=MGTDAHQEBWWYKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380925   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380925(Ethanesulfonic acid [8-(3-chloro-1H- indazol-6-yl)...)
Affinity DataIC50: 45.9nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent