BDBM380937 8-(4,4-Difluoro-chroman-6-yl)-3,4- dihydro-1H-pyrano[4,3-c]pyridin-4-ol, Enantiomer II::US9890171, 141::US9890171, 142

SMILES OC1COCc2c1cncc2-c1ccc2OCCC(F)(F)c2c1

InChI Key InChIKey=IMBZHYUGNZLUQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380937   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380937(US9890171, 142 | 8-(4,4-Difluoro-chroman-6-yl)-3,4...)
Affinity DataIC50: 118nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380937(US9890171, 142 | 8-(4,4-Difluoro-chroman-6-yl)-3,4...)
Affinity DataIC50: 339nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent