BDBM380950 N-[8-(2-Oxo-2H-chromen-6-yl)-3,4- dihydro-1H-pyrano[4,3-c]pyridin-4- yl]-acetamide, Enantiomer II::US9890171, 154

SMILES CC(=O)NC1COCc2c1cncc2-c1ccc2oc(=O)ccc2c1

InChI Key InChIKey=YIVJUNDOLWHTED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380950   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380950(N-[8-(2-Oxo-2H-chromen-6-yl)-3,4- dihydro-1H-pyran...)
Affinity DataIC50: 26.3nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent