BDBM380952 N-[8-(3-Methyl-benzo[d]isoxazol-5- yl)-3,4-dihydro-1H- pyrano[4,3-c]pyridin-4-yl]- propionamide, Enantiomer I::US9890171, 156

SMILES CCC(=O)NC1COCc2c1cncc2-c1ccc2onc(C)c2c1

InChI Key InChIKey=YINLZJGHPAJVAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380952   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380952(N-[8-(3-Methyl-benzo[d]isoxazol-5- yl)-3,4-dihydro...)
Affinity DataIC50: 312nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent