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BDBM38184 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-((2-(nicotinamido)ethyl)sulfonyl)-1H-indole-2-carboxamide::US10093640, Example 155::US10844032, Example 155
SMILES: Cc1cc(OCCCc2c([nH]c3ccccc23)C(=O)NS(=O)(=O)CCNC(=O)c2cccnc2)cc(C)c1Cl
InChI Key: InChIKey=QQAGACINVSRVMV-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 (Human) | BDBM38184![]() (US10093640, Example 155 | 3-(3-(4-chloro-3,5-dimet...) | GoogleScholar | UniChem | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Induced myeloid leukemia cell differentiation protein Mcl-1 [172-327] (Human) | BDBM38184![]() (US10093640, Example 155 | 3-(3-(4-chloro-3,5-dimet...) | GoogleScholar | UniChem | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||