BDBM382173 (1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid::US10273259, Example 1::US10711020, Example 1

SMILES: c1cc(ccc1F)S(=O)(=O)[C@@]23CCN([C@@H]2CCc4c3ccc(c4)C(C(F)(F)F)(C(F)(F)F)F)C(=O)C5CCC(CC5)C(=O)O

InChI Key: InChIKey=FEJZVGPREBSBIT-UHFFFAOYSA-N

Data: 7 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 382173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Mouse)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma [262-507] (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-beta (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-alpha (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM382173 ((1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair