BDBM384192 4-(6-(4-Amino-4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-b]pyrazin-3-yl)-3-chloro-N-methylpyridin-2-amine::US10280171, Example 112::US10851110, Example 112::US11466017, Example 112

SMILES: CNc1nccc(-c2n[nH]c3nc(cnc23)N2CCC(C)(N)CC2)c1Cl

InChI Key: InChIKey=XLKDUTBYZJONNW-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 384192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM384192 (US10280171, Example 112 | 4-(6-(4-Amino-4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair