BDBM384803 US10285989, Example 19

SMILES C[C@@H](NC(=O)c1cc(=O)[nH]c(Oc2ccccc2)n1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DWQMRKAPYIPUMN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384803   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384803(US10285989, Example 19)
Affinity DataKi:  2.93E+3nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent