BDBM384819 N-[(1R)-1-(4-cyclopropylphenyl)-2,2- dimethylpropyl]-2-(dimelhylamino)-6- oxo-1,6-dihydropyrimidine-4- carboxamide::US10285989, Example 35
SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)N[C@@H](c1ccc(cc1)C1CC1)C(C)(C)C
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 384819
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.110nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair