BDBM384988 2-(dimethylamino)-N-{(1S)-1-[3- fluoro-4- (trifluoromethoxy)phenyl]-2- hydroxy-2-methylpropyl}-6-oxo- 1,6-dihydropyrimidine-4- carboxamide::US10285989, Example 208
SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)C(C)(C)O
InChI Key
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384988
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.120nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair