BDBM385660 5-(4-cyanophenyl)-N- (oxetan-3-yl)- [1,2,4]triazolo[1,5- a]pyridine-7- carboxamide::US10287286, Example 68

SMILES O=C(NC1COC1)c1cc(-c2ccc(cc2)C#N)n2ncnc2c1

InChI Key InChIKey=GQZLLNMBCOFNNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385660   

TargetProlyl hydroxylase EGLN2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM385660(5-(4-cyanophenyl)-N- (oxetan-3-yl)- [1,2,4]triazol...)
Affinity DataIC50: 1.89E+3nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
US Patent