BDBM386067 US10287305, Example 5::US10508083, Example 191::US11292766, Example 191::methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis-4- phenylcyclohexyl)oxy)methyl)- piperidine-1-carboxylate

SMILES: COC(=O)N1CCC[C@@H]([C@@H]1COC2CCC(CC2)c3ccccc3)NS(=O)(=O)C

InChI Key: InChIKey=UXZAJSZFFARTEI-UHFFFAOYSA-N

Data: 12 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 386067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM386067 (methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair