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BDBM387376 N3-(3-Bromo-4- methylphenyl) furo[2,3-c] pyridine-2,3- diamine::US10294212, No. 21

SMILES: Cc1ccc(Nc2c(N)oc3cnccc23)cc1Br

InChI Key: InChIKey=IZWPLSJHJACDNP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387376   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM387376
PNG
(N3-(3-Bromo-4- methylphenyl) furo[2,3-c] pyridine-...)
Show SMILES Cc1ccc(Nc2c(N)oc3cnccc23)cc1Br
Show InChI InChI=1S/C14H12BrN3O/c1-8-2-3-9(6-11(8)15)18-13-10-4-5-17-7-12(10)19-14(13)16/h2-7,18H,16H2,1H3
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MMDB

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US Patent
n/an/a 600n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...


US Patent US10294212 (2019)


BindingDB Entry DOI: 10.7270/Q24M96V5
More data for this
Ligand-Target Pair