BDBM38871 (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine;hydrochloride::EMETINE HYDROCHLORIDE::MLS000028478::SMR000058444::cid_6603320::med.21724, Compound Emetine

SMILES: CC[C@H]1CN2CCc3cc(c(cc3[C@@H]2C[C@@H]1C[C@@H]4c5cc(c(cc5CCN4)OC)OC)OC)OC

InChI Key: InChIKey=AUVVAXYIELKVAI-UHFFFAOYSA-N

Data: 7 IC50  4 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 38871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
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Steroidogenic factor 1 (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	357	n/a	n/a	n/a	n/a	n/a	n/a
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Steroidogenic factor 1 (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock factor protein 1 (Mouse)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<160	n/a	n/a	n/a	n/a
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Bcl-2-like protein 11 (Human)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM38871 (cid_6603320 | SMR000058444 | EMETINE HYDROCHLORIDE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
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