BDBM389631 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide::US11345695, Example 3::US11840513, Example 3::US9951056, Example 3

SMILES: NC(=O)c1ccc(nc1-c1ccc(Oc2ccccc2)cc1)C1CCN(CC1)C(=O)C=C

InChI Key: InChIKey=MZPVEMOYADUARK-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 389631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM389631 (US9951056, Example 3 | 6-(1-acryloylpiperidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair