BDBM390134 N-{2-[2-(4-Methylpiperazin-1-yl)-2-oxoethyl]-2H-indazol-5-yl}-6′-nitro-2,3′-bipyridine-6-carboxamide::US9951086, Example 26

SMILES CN1CCN(CC1)C(=O)Cn1cc2cc(NC(=O)c3cccc(n3)-c3ccc(nc3)[N+]([O-])=O)ccc2n1

InChI Key InChIKey=RPRLYGBWFIPIIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 390134   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM390134(N-{2-[2-(4-Methylpiperazin-1-yl)-2-oxoethyl]-2H-in...)
Affinity DataIC50: 1.62E+3nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent