BDBM391565 4-(cyclopropylmethyl)-2- isopropyl-8-(6-methyl-7-oxo- 6,7-dihydro-1H-pyrrolo[2,3- c]pyridin-4-yl)-6- (methyslulfonyl)-2H-1,4- benzoxazin-3(4H)-one::US9957268, Example 53

SMILES Cn1cc(-c2cc(cc3NC(=O)C(CC4CC4)Oc23)S(C)(=O)=O)c2cc[nH]c2c1=O

InChI Key InChIKey=FJUFHVLFNKLQTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391565   

TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent
LigandPNGBDBM391565(US9957268, Example 53 | 4-(cyclopropylmethyl)-2- i...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandPNGBDBM391565(US9957268, Example 53 | 4-(cyclopropylmethyl)-2- i...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent