BDBM391566 4-ethyl-2-isopropyl-8-(6- methyl-7-oxo-6,7-dihydro- 1H-pyrrolo[2,3-c]pyridin-4- yl)-6-(methylsulfonyl)-2H- 1,4-benzoxazin-3(4H)-one::US9957268, Example 54

SMILES CCC1Oc2c(NC1=O)cc(cc2-c1cn(C)c(=O)c2[nH]ccc12)S(C)(=O)=O

InChI Key InChIKey=IPBHYXMGQCOPTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391566   

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandPNGBDBM391566(US9957268, Example 54 | 4-ethyl-2-isopropyl-8-(6- ...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent
LigandPNGBDBM391566(US9957268, Example 54 | 4-ethyl-2-isopropyl-8-(6- ...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent