BDBM39346 (2S)-2-amino-3-mercapto-3-methyl-butyric acid;hydrochloride::(2S)-2-amino-3-mercapto-3-methylbutanoic acid;hydrochloride::(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid;hydrochloride::(2S)-2-azanyl-3-methyl-3-sulfanyl-butanoic acid;hydrochloride::Cuprenil::D(-)PENICILLAMINE HYDROCHLORIDE::Depen::MLS000028669::Penicillamine::SMR000058903::cid_92173

SMILES CC(C)(S)[C@@H](N)C(O)=O

InChI Key InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39346   

TargetGenome polyprotein(West Nile virus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM39346((2S)-2-amino-3-mercapto-3-methyl-butyric acid;hydr...)
Affinity DataIC50:  5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCystathionine gamma-lyase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM39346((2S)-2-amino-3-mercapto-3-methyl-butyric acid;hydr...)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM39346((2S)-2-amino-3-mercapto-3-methyl-butyric acid;hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM39346((2S)-2-amino-3-mercapto-3-methyl-butyric acid;hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed