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BDBM394644 3-[(2-{[1-(pyrimidin-5-yl)cyclopropyl]amino}pyrimidin-5-yl)carbonyl]benzonitrile::US10308615, Example 1

SMILES: O=C(c1cnc(NC2(CC2)c2cncnc2)nc1)c1cccc(c1)C#N

InChI Key: InChIKey=OJUWWGHSEBTYGS-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 394644
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Pantetheinase (Human)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Pantetheinase (Human)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Pantetheinase (Human)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Pantetheinase (Mouse)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Pantetheinase (Human)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Biotinidase (Human)	BDBM394644 (US10308615, Example 1 \| 3-[(2-{[1-(pyrimidin-5-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair