BDBM395297 N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide::US10308634, Example 12::US10793545, Example 12::US11992481, Example 12::US12006303, Example 12

SMILES: CC(C)(O)c1cc2nn(CCS(C)(=O)=O)cc2cc1NC(=O)c1cccc(n1)C(F)(F)F

InChI Key: InChIKey=OQAMEEFUUFJZRS-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 395297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM395297 (N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair