BDBM395571 (R)-4-((7-cyano-2- (3'-(3-((3-hydroxy pyrrolidin-1-yl)- methyl)-1,7- naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl- 3-yl)benzo [d]- oxazol-5-yl)methyl-::US10308644, Example 183::US10800768, Example 183::US11339149, Example 183

SMILES Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC45CCC(CC4)(C5)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=YSKWTRXRJQZZAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395571   

LigandPNGBDBM395571(US10308644, Example 183 | (R)-4-((7-cyano-2- (3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395571(US10308644, Example 183 | (R)-4-((7-cyano-2- (3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395571(US10308644, Example 183 | (R)-4-((7-cyano-2- (3'-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent