BDBM395583 (R)-1-((7-cyano-2-(3'- (3-(((S)-1-hydroxy- propan-2-ylamino)- methyl)-1,7- naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]oxazol-::US10308644, Example 195::US10800768, Example 195::US11339149, Example 195

SMILES C[C@@H](CO)NCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)nccc2c1

InChI Key InChIKey=YHYYDECZKFTANU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395583   

LigandPNGBDBM395583(US10308644, Example 195 | (R)-1-((7-cyano-2-(3'- (...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395583(US10308644, Example 195 | (R)-1-((7-cyano-2-(3'- (...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395583(US10308644, Example 195 | (R)-1-((7-cyano-2-(3'- (...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent