BDBM395601 (S)-1-((8-(3'-(7- cyano-5-((2- hydroxypropyl amino)methyl)- benzo[d]oxazol- 2-yl)-2,2'- dimethylbiphenyl- 3-ylamino)-1,7-::US10308644, Example 212::US10800768, Example 212::US11339149, Example 212

SMILES C[C@H](O)CNCc1cc(C#N)c2oc(nc2c1)-c1cccc(c1C)-c1cccc(Nc2nccc3cc(CN4CCCCC4)cnc23)c1C

InChI Key InChIKey=DAFMETCDYUJWPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395601   

LigandPNGBDBM395601(US10308644, Example 212 | (S)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395601(US10308644, Example 212 | (S)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395601(US10308644, Example 212 | (S)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent