BDBM399865 N-(1-(5-(2-chloro-4-(2-oxo-2- (pyrrolidin-1- yl)ethoxy)benzyl)octahydropyrrolo[3,4- c]pyrrole-2-carbonyl)-1H-pyrazol-4-yl)- N-methylacetamide::US10323038, Example 189

SMILES CN(C(C)=O)c1cnn(c1)C(=O)N1CC2CN(Cc3ccc(OCC(=O)N4CCCC4)cc3Cl)CC2C1

InChI Key InChIKey=SWOHCYNRGXMVIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 399865   

TargetFatty-acid amide hydrolase 1(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399865(US10323038, Example 189 | N-(1-(5-(2-chloro-4-(2-o...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399865(US10323038, Example 189 | N-(1-(5-(2-chloro-4-(2-o...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent