BDBM399886 N-methyl-N-(1-(4-(2-(pyrrolidin-1-yl)-4- (trifluoromethyl)benzyl)piperazine-1- carbonyl)-1H-pyrazol-4- yl)methanesulfonamide::US10323038, Example 218

SMILES CN(c1cnn(c1)C(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1)S(C)(=O)=O

InChI Key InChIKey=ZBZYFGRLZFZNEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 399886   

TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399886(US10323038, Example 218 | N-methyl-N-(1-(4-(2-(pyr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399886(US10323038, Example 218 | N-methyl-N-(1-(4-(2-(pyr...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent