BDBM404057 US10336717, Compound 350

SMILES COCC(C)N1C(N)=N[C@@]2(C1=O)c1cc(CCC3CC3)ccc1CC21CCC(CC1)OC

InChI Key InChIKey=MVNFTSJOKCJMGW-DZKNABIYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404057   

TargetBeta-secretase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM404057(US10336717, Compound 350)
Affinity DataIC50:  482nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent