BDBM410466 US10377770, Example 288::US10377770, Example 289

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(C)(F)F)cc1-c1cnc2N(CC(C)(C)O)C(=O)C[C@@H]3COCCN3c2c1

InChI Key InChIKey=MDWSTTSQZZARSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410466   

LigandPNGBDBM410466(US10377770, Example 289 | US10377770, Example 288)
Affinity DataIC50: 0.900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410466(US10377770, Example 289 | US10377770, Example 288)
Affinity DataIC50: 0.900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent