BDBM410474 US10377770, Example 296::US10377770, Example 298

SMILES CCN1c2ncc(cc2C2CCOCC2OC1=O)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)cnc1C

InChI Key InChIKey=HXWLGKGLFONOGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410474   

LigandPNGBDBM410474(US10377770, Example 298 | US10377770, Example 296)
Affinity DataIC50: 0.300nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410474(US10377770, Example 298 | US10377770, Example 296)
Affinity DataIC50: 1.80nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent