BDBM413842 4-({(2S)-2-[4-{5-Chloro-2-[4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl]phenyl}-5-methoxy-2-oxopyridin-1(2H)-yl]butanoyl}amino)-2-fluorobenzamide (Enantiomer 2)::US10421742, Example 235::US11180471, Example 235::US20250051303, Example 1

SMILES: CC[C@@H](C(=O)Nc1ccc(C(N)=O)c(F)c1)n1cc(OC)c(cc1=O)-c1cc(Cl)ccc1-n1cc(nn1)C(F)(F)F

InChI Key: InChIKey=XYWIPYBIIRTJMM-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 413842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
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Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Plasma kallikrein (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor XI (Human)	BDBM413842 (US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair