BDBM415570 (2R,3S,4R,5R)-2-(4-fluorobenzyl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (YY-7)::US10428104, Example 100

SMILES Cc1ncnc2n(ccc12)[C@@H]1O[C@H](Cc2ccc(F)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=OAPGBCGMOQYGRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415570   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM415570(US10428104, Example 100 | (2R,3S,4R,5R)-2-(4-fluor...)
Affinity DataIC50: 90nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent