BDBM415592 US10428108, Example 4

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1cccc(Cl)c1)C(=O)C(F)(F)C(=O)NCCC(F)(F)F

InChI Key InChIKey=LWDNDBXNMKHZGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415592   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM415592(US10428108, Example 4)
Affinity DataIC50: 420nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent