BDBM417498 US10457669, Example 112::US11001575, Example 112

SMILES Clc1cnc(NC2CCOCC2)nc1-c1ccc2CN(CCOC3CCCC3)C(=O)c2c1

InChI Key InChIKey=FRNFQTNBPOLIDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417498   

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417498(US10457669, Example 112 | US11001575, Example 112)
Affinity DataIC50: 19nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417498(US10457669, Example 112 | US11001575, Example 112)
Affinity DataIC50: 19nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent