BDBM419127 3CLpro inhibitor 6e
SMILES CCCCC1CCC(CC1)OC(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC1CCNC1=O)C(O)S([O-])(=O)=O
InChI Key InChIKey=WKNCKKOHQQLNCY-PTFNDWLJSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 419127
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair