BDBM420133 (4-{[2-(Dimethylamino)ethyl](methyl)amino}piperidin-1-yl)[(7S)-4-(pyrazolo[1,5-a]pyridin-5-ylamino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-7-yl]methanone::US10487092, Example 40

SMILES CN(C)CCN(C)C1CCN(CC1)C(=O)[C@H]1CCc2c(C1)sc1ncnc(Nc3ccn4nccc4c3)c21

InChI Key InChIKey=XJVYEWNWRRHFGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420133   

LigandPNGBDBM420133((4-{[2-(Dimethylamino)ethyl](methyl)amino}piperidi...)
Affinity DataIC50: 6nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent