BDBM420134 US10487092, Example 41::[(3S)-3-(Dimethylamino)pyrrolidin-1-yl][(7S)-4-(pyrazolo[1,5-a]pyridin-5-ylamino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-7-yl]methanone

SMILES CN(C)[C@H]1CCN(C1)C(=O)[C@H]1CCc2c(C1)sc1ncnc(Nc3ccn4nccc4c3)c21

InChI Key InChIKey=YNZLRXOJWFYQRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420134   

LigandPNGBDBM420134([(3S)-3-(Dimethylamino)pyrrolidin-1-yl][(7S)-4-(py...)
Affinity DataIC50: 11nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
9/20/2020
Entry Details
US Patent