BDBM420148 US10485800, Cmpd ID 6-(4-amino-3- methoxyphenyl)-1- cyclopentyl- 1H- imidazo[4,5- b]pyrazin- 2(3H)-one::US10485800, Example 118

SMILES COc1cc(ccc1N)-c1cnc2[nH]c(=O)n(C3CCCC3)c2n1

InChI Key InChIKey=IHZDEPOFNJDDRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420148   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
The University of Rochester

US Patent
LigandPNGBDBM420148(US10485800, Cmpd ID 6-(4-amino-3- methoxyphenyl)-1...)
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent