BDBM420907 US10479784, Compound III-35::US10961232, Compound III-35

SMILES CN(C)[C@H]1CCN(C1)C(=O)c1ccc(cc1F)-c1cnc(N)c(n1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=VDHCADNQGXLIMN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420907   

TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM420907(US10479784, Compound III-35 | US10961232, Compound...)
Affinity DataKi:  55nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM420907(US10479784, Compound III-35 | US10961232, Compound...)
Affinity DataKi:  55nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent