BDBM4213 6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4-yl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD173952

SMILES: Cn1c2nc(Nc3ccc(cc3)N3CCOCC3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key: InChIKey=XZEJMVDCQZRHLN-UHFFFAOYSA-N

Data: 5 KI  11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 4213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.35	n/a	n/a	n/a	n/a	7.5	25
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Fibroblast growth factor receptor 1 (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	98.8	n/a	n/a	n/a	n/a	7.4	25
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Platelet-derived growth factor receptor beta (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	636	n/a	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase Lck (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM4213 (6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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